What is Hypoparathyroidism?
Hypoparathyroidism is a rare disease caused by an absent or low level of PTH (parathyroid hormone) in the body.
PTH is produced in the parathyroid glands of your neck, and it plays an important role in maintaining your body’s mineral balance (calcium and phosphate).
Sites of PTH action
PTH tells your kidneys to keep calcium and remove phosphate
PTH activates vitamin D that helps your body absorb calcium in the gut
PTH helps your bones release calcium
How common is hypoparathyroidism?
Information on the prevalence of hypoparathyroidism is limited, but recent estimates are:
- 24 per 100,000 inhabitants in Denmark
- 10.2 per 100,000 inhabitants in Norway
- 25-37 per 100,000 population in the US